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Chronic Nerve Pain in Feet: How Sanexas Therapy Provides Relief When Other Treatments Fail

Dr. Eman Elmi
June 23, 2025
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Chronic nerve pain in the feet, also known as peripheral neuropathy, affects millions of Americans, causing symptoms ranging from mild discomfort to debilitating pain that significantly impacts quality of life. For many patients, finding effective relief can be a frustrating journey of trial and error, with conventional treatments often providing limited or temporary benefits.

At Diablo Foot & Ankle, we specialize in advanced treatments for chronic foot pain, including Sanexas Electrotherapy—an innovative, non-invasive approach that has proven effective for many patients who haven't found relief through traditional methods. This comprehensive guide explores how Sanexas works, why it succeeds where other treatments fail, and what patients can expect from this breakthrough therapy.

Understanding Chronic Nerve Pain in the Feet

Before discussing treatment options, it's important to understand the nature of chronic nerve pain and why it can be so challenging to treat.

What Causes Nerve Pain in the Feet?

Peripheral neuropathy in the feet can result from various conditions:

Diabetes: The most common cause, affecting up to 50% of people with diabetes Chemotherapy: Many cancer treatments damage peripheral nerves Autoimmune disorders: Conditions like rheumatoid arthritis and lupus Infections: Shingles, Lyme disease, and other infections Trauma: Physical injury to nerves Vitamin deficiencies: Particularly B vitamins Alcoholism: Long-term alcohol abuse damages nerves Medications: Certain drugs have neurotoxic side effects Idiopathic neuropathy: No identifiable cause (approximately 30% of cases)

The Progression of Nerve Damage

Nerve pain typically develops in stages:

Early stage:

  • Intermittent tingling or pins-and-needles sensations
  • Mild numbness
  • Heightened sensitivity
  • Symptoms that come and go

Intermediate stage:

  • More persistent numbness
  • Regular burning or shooting pain
  • Difficulty with balance
  • Symptoms that interfere with sleep and daily activities

Advanced stage:

  • Constant pain and numbness
  • Significant impact on mobility
  • Potential for wounds and infections due to lack of sensation
  • Substantial decrease in quality of life

Why Nerve Pain Is Difficult to Treat

Several factors make nerve pain particularly challenging to address:

Complex mechanisms: Nerve pain involves multiple physiological pathways Self-perpetuating: Damaged nerves become increasingly sensitive Variable response: Patients respond differently to the same treatments Progressive nature: Underlying conditions often continue to damage nerves Medication resistance: Many patients develop tolerance to pain medications Systemic effects: Nerve damage affects circulation, muscle function, and tissue health

Conventional Treatments and Their Limitations

Most patients with chronic nerve pain have tried multiple conventional treatments before seeking advanced options like Sanexas. Understanding these traditional approaches and their limitations helps explain why alternative therapies are often necessary.

Medication-Based Approaches

Analgesics (Pain Relievers):

  • Over-the-counter options like acetaminophen and NSAIDs
  • Prescription-strength anti-inflammatory medications
  • Limitations: Often ineffective for nerve pain; side effects with long-term use; doesn't address underlying nerve damage

Anticonvulsants:

  • Medications like gabapentin and pregabalin
  • Limitations: Side effects including dizziness and drowsiness; diminishing effectiveness over time; doesn't promote nerve healing

Antidepressants:

  • Tricyclic antidepressants and SNRIs
  • Limitations: Side effects like dry mouth, weight gain, and sedation; incomplete pain relief; doesn't address nerve regeneration

Opioids:

  • Reserved for severe, intractable pain
  • Limitations: Risk of dependence; tolerance development; significant side effects; increasingly restricted prescribing

Topical Treatments

Lidocaine patches and creams:

  • Provide localized numbing
  • Limitations: Temporary relief; doesn't penetrate deeply enough for many nerve conditions; inconvenient for daily use

Capsaicin:

  • Derived from hot peppers to desensitize nerves
  • Limitations: Initial burning sensation; variable effectiveness; requires consistent application

Interventional Procedures

Nerve blocks:

  • Injection of anesthetic near affected nerves
  • Limitations: Temporary relief; requires repeated procedures; potential complications

Spinal cord stimulation:

  • Implanted device that masks pain signals
  • Limitations: Invasive; expensive; not suitable for all patients; addresses symptoms rather than causes

Physical Approaches

Physical therapy:

  • Exercises to improve strength, flexibility, and circulation
  • Limitations: Limited direct effect on nerve damage; results take time; requires ongoing commitment

TENS units:

  • Low-level electrical stimulation to block pain signals
  • Limitations: Temporary relief only during use; doesn't promote healing; limited depth of penetration

Lifestyle Modifications

Blood sugar control for diabetic neuropathy:

  • Crucial for preventing progression
  • Limitations: Doesn't reverse existing damage; requires strict adherence

Nutritional supplements:

  • B vitamins, alpha-lipoic acid, etc.
  • Limitations: Modest benefits; works slowly; variable effectiveness

Introducing Sanexas Electrotherapy: A Different Approach

Sanexas represents a fundamental shift in treating chronic nerve pain—moving beyond symptom management to address the underlying causes of nerve dysfunction.

What Is Sanexas?

Sanexas is an FDA-cleared, non-invasive treatment that uses Electric Cell Signaling Treatment (EST) to deliver sophisticated electronic signals through electrodes placed on the skin. Unlike basic TENS units that simply block pain signals, Sanexas works at the cellular level to promote actual healing and restoration of nerve function.

The Science Behind Sanexas

Sanexas technology is based on advanced research in bioelectronic medicine and cellular physiology:

Quantum-Based Electronic Signaling:

  • Delivers complex waveforms across a wide frequency spectrum (1-20,000 Hz)
  • Penetrates deeply into tissues, reaching nerves that other treatments cannot
  • Mimics and enhances the body's natural electrical signaling systems

Cellular Effects:

  • Increases cell membrane permeability
  • Enhances cellular metabolism and energy production
  • Promotes ion exchange across cell membranes
  • Stimulates cellular repair mechanisms

Nerve-Specific Benefits:

  • Reduces abnormal firing of damaged nerves
  • Promotes regeneration of nerve fibers
  • Restores normal nerve signal transmission
  • Decreases inflammation around nerve tissues

Vascular Improvements:

  • Enhances local blood flow
  • Improves oxygen delivery to tissues
  • Facilitates removal of metabolic waste products
  • Supports the microenvironment needed for healing

How Sanexas Differs from Other Electrical Therapies

Many patients have tried TENS units or other electrical stimulation devices with limited success. Sanexas is fundamentally different:

TENS Units:

  • Simple, single-frequency electrical current
  • Works primarily by blocking pain signals
  • Limited depth of penetration
  • Temporary relief only during use
  • No significant cellular effects

Sanexas:

  • Complex, variable frequency electronic signals
  • Works by promoting actual cellular healing
  • Deep tissue penetration
  • Cumulative, lasting benefits
  • Significant cellular and tissue effects

Interferential Current (IFC):

  • Uses two medium-frequency currents
  • Primarily focuses on pain reduction
  • Limited cellular effects
  • Moderate tissue penetration

Sanexas:

  • Uses quantum-based electronic signaling
  • Addresses both pain and underlying causes
  • Comprehensive cellular effects
  • Superior tissue penetration

Why Sanexas Succeeds Where Other Treatments Fail

For patients who haven't found relief through conventional approaches, Sanexas offers several distinct advantages that explain its effectiveness:

1. Addresses Multiple Aspects of Nerve Dysfunction

Chronic nerve pain involves complex, interrelated problems:

  • Damaged nerve fibers
  • Impaired cellular metabolism
  • Reduced microcirculation
  • Chronic inflammation
  • Abnormal signal transmission

While most treatments target only one aspect (typically pain signals), Sanexas addresses all these factors simultaneously, creating a comprehensive healing environment.

2. Reaches the Source of the Problem

Many treatments cannot effectively reach the affected nerves:

  • Oral medications are diluted throughout the body
  • Topical treatments have limited penetration
  • Basic electrical therapies affect primarily surface tissues

Sanexas delivers therapeutic signals directly to the affected nerves, even those deep within the tissues, ensuring the treatment reaches where it's needed most.

3. Promotes Actual Healing Rather Than Masking Symptoms

Most conventional treatments focus on blocking pain signals or temporarily reducing symptoms. Sanexas is different:

  • Stimulates cellular repair mechanisms
  • Enhances natural healing processes
  • Addresses underlying causes of nerve dysfunction
  • Works toward restoring normal nerve function

4. Avoids Medication Side Effects and Risks

Many patients seek alternatives to medication-based approaches due to:

  • Concerns about side effects
  • Medication interactions
  • Diminishing effectiveness over time
  • Dependency issues with certain medications

Sanexas provides a drug-free alternative that doesn't carry these risks.

5. Offers Cumulative, Progressive Benefits

Unlike treatments that provide only temporary relief, Sanexas benefits build over time:

  • Each session enhances the effects of previous treatments
  • Improvements often continue after the treatment course ends
  • Many patients experience long-term relief
  • Some achieve permanent improvement in nerve function

The Sanexas Treatment Experience

Patients considering Sanexas often want to know what to expect during treatment. At Diablo Foot & Ankle, we've designed a patient-centered process to ensure comfort and optimal results.

Initial Evaluation

Before beginning Sanexas therapy, patients undergo a comprehensive assessment:

  • Detailed medical history review
  • Evaluation of previous treatments and their effectiveness
  • Physical examination focusing on neurological function
  • Discussion of symptoms and their impact on quality of life
  • Development of personalized treatment goals

Treatment Protocol

Based on your specific condition, we'll develop a customized treatment plan:

  • Typically 6-12 sessions, depending on severity and response
  • Sessions usually scheduled 2-3 times per week
  • Each session lasting approximately 30-45 minutes
  • Periodic reassessment to track progress and adjust parameters

During the Session

The Sanexas treatment experience is comfortable and straightforward:

  1. You'll be comfortably seated or reclined
  2. The treatment area will be cleaned
  3. Electrode pads will be placed on specific locations on your feet and legs
  4. The Sanexas device will be programmed with your customized treatment parameters
  5. You'll feel a gentle tingling or vibrating sensation as the treatment begins
  6. The intensity will be adjusted to your comfort level
  7. You can relax, read, or even nap during the treatment

Most patients describe the sensation as pleasant or barely noticeable. There's no pain involved, and many find the sessions relaxing.

After Treatment

Following each session:

  • No downtime or recovery period
  • Immediate return to normal activities
  • No medication restrictions
  • No special precautions needed

Expected Results and Timeline

While individual responses vary, most patients follow a typical progression:

After 1-3 sessions:

  • Initial reduction in pain intensity
  • Brief periods of improved sensation
  • Beginning awareness of changes in foot comfort

After 4-6 sessions:

  • More consistent pain relief
  • Longer periods of comfort between treatments
  • Improved sleep due to reduced nighttime symptoms
  • Noticeable improvement in sensation

After 7-12 sessions:

  • Significant reduction in pain levels
  • Substantial improvement in sensation and function
  • Decreased reliance on pain medications
  • Enhanced mobility and quality of life

Long-term outcomes:

  • Many patients maintain improvements for months or years
  • Some require occasional maintenance sessions
  • A percentage achieve permanent improvement
  • Most experience significant enhancement in quality of life

Case Studies: Success Stories from Diablo Foot & Ankle

While individual results vary, these anonymized case examples illustrate typical outcomes for patients who have tried Sanexas after other treatments failed:

Case 1: Diabetic Neuropathy Resistant to Medication

Patient Profile:

  • 67-year-old male with 15-year history of type 2 diabetes
  • Severe burning pain and numbness in both feet
  • Previously tried gabapentin, pregabalin, and duloxetine with limited relief
  • Significant sleep disruption and mobility limitations

Treatment:

  • 12 Sanexas sessions over 6 weeks
  • Combined with nutritional support and foot care education

Outcome:

  • 70% reduction in pain intensity
  • Significant improvement in sleep quality
  • Reduced medication requirements
  • Restored ability to walk for exercise
  • Maintenance sessions every 2-3 months

Case 2: Chemotherapy-Induced Neuropathy

Patient Profile:

  • 58-year-old female breast cancer survivor
  • Developed severe neuropathy after taxane chemotherapy
  • Tried multiple medications with intolerable side effects
  • Pain described as "walking on broken glass"

Treatment:

  • 10 Sanexas sessions over 5 weeks
  • Integrated with gentle physical therapy

Outcome:

  • 80% improvement in pain levels
  • Restored normal sensation in several areas
  • Eliminated need for pain medication
  • Returned to previously enjoyed activities
  • No recurrence of symptoms at one-year follow-up

Case 3: Post-Surgical Nerve Pain

Patient Profile:

  • 42-year-old male with persistent nerve pain following foot surgery
  • Two years of failed treatments including nerve blocks and opioids
  • Diagnosed with Complex Regional Pain Syndrome (CRPS)
  • Unable to wear normal shoes or return to work

Treatment:

  • 16 Sanexas sessions over 8 weeks
  • Combined with desensitization therapy and custom orthotics

Outcome:

  • Progressive improvement throughout treatment
  • 90% reduction in allodynia (pain from light touch)
  • Successful return to regular footwear
  • Resumed full-time employment
  • Occasional maintenance treatment for flare-ups

Integrating Sanexas with Other Therapies

At Diablo Foot & Ankle, we often combine Sanexas with complementary approaches for optimal results:

Nutritional Support

Certain nutrients are essential for nerve health and repair:

  • Alpha-lipoic acid: A powerful antioxidant that improves nerve function
  • B-complex vitamins: Essential for nerve health and repair
  • Omega-3 fatty acids: Help reduce inflammation
  • Magnesium: Supports proper nerve function
  • Vitamin D: Important for nerve and muscle function

Physical Therapy

Targeted exercises can enhance Sanexas results:

  • Improve circulation to affected areas
  • Maintain muscle strength and flexibility
  • Enhance proprioception and balance
  • Prevent compensatory movement patterns

Custom Orthotics

Specially designed shoe inserts can:

  • Reduce mechanical pressure on sensitive nerves
  • Improve foot alignment and function
  • Enhance comfort during daily activities
  • Prevent secondary problems from altered gait

Lifestyle Modifications

Certain changes can support nerve healing:

  • Blood sugar management for diabetic patients
  • Smoking cessation to improve circulation
  • Alcohol reduction to prevent further nerve damage
  • Appropriate exercise to enhance circulation
  • Stress management techniques

Is Sanexas Right for You?

While Sanexas has helped many patients with treatment-resistant nerve pain, determining if it's appropriate for your specific situation requires professional evaluation.

Ideal Candidates

Sanexas may be particularly beneficial if you:

  • Have not achieved adequate relief from conventional treatments
  • Wish to reduce reliance on pain medications
  • Have been diagnosed with peripheral neuropathy
  • Experience burning, tingling, or numbness in your feet
  • Have diabetes, chemotherapy history, or other known causes of nerve damage

Considerations

Factors that might influence the decision include:

  • Your specific diagnosis and symptom pattern
  • Duration and severity of your condition
  • Previous treatments and their effectiveness
  • Presence of other medical conditions
  • Your treatment goals and expectations

Contraindications

Sanexas may not be appropriate for patients with:

  • Implanted electronic devices like pacemakers
  • Pregnancy
  • Active cancer in the treatment area
  • Certain seizure disorders

During your consultation at Diablo Foot & Ankle, our specialists will carefully evaluate your situation to determine if Sanexas is right for you.

Insurance Coverage and Cost Considerations

Many patients are concerned about the financial aspects of treatment:

Insurance Coverage

  • Many insurance plans, including Medicare, now cover Sanexas therapy for neuropathy when medically necessary
  • Coverage varies by plan and diagnosis
  • Our staff will verify your benefits before treatment begins
  • We'll explain any out-of-pocket costs upfront

Value Considerations

When evaluating treatment options, consider:

  • The cost of continuing with ineffective treatments
  • Expenses related to pain medications and their side effects
  • The impact of chronic pain on work productivity
  • The value of improved quality of life
  • The potential to reduce other healthcare costs

Getting Started with Sanexas at Diablo Foot & Ankle

If you're struggling with chronic nerve pain in your feet that hasn't responded to other treatments, here's how to explore whether Sanexas might help:

  1. Schedule a consultation: Call our office at (925) 464-1982 to arrange an evaluation with one of our specialists.

  1. Comprehensive assessment: During your initial visit, we'll conduct a thorough examination, review your treatment history, and discuss your symptoms and goals.

  1. Personalized treatment plan: If Sanexas is appropriate for your condition, we'll develop a customized treatment protocol designed to address your specific needs.

  1. Coordinated care: We'll work with your other healthcare providers to ensure a comprehensive approach to your nerve pain.

  1. Ongoing support: Throughout your treatment and beyond, our team will provide guidance on maintaining and enhancing your results.

Conclusion

Chronic nerve pain in the feet can be devastating, affecting every aspect of daily life. When conventional treatments fail to provide adequate relief, advanced options like Sanexas Electrotherapy offer new hope. By addressing the underlying causes of nerve dysfunction rather than simply masking symptoms, Sanexas has helped many patients achieve significant, lasting improvement in their condition.

At Diablo Foot & Ankle, we understand the frustration and limitations that chronic nerve pain can cause. Our specialists are committed to providing the most advanced, effective treatments available to help our patients regain comfort, function, and quality of life.

Don't resign yourself to living with chronic nerve pain or continuing treatments that aren't working. Contact Diablo Foot & Ankle today at (925) 464-1982 to learn if Sanexas therapy might be the solution you've been searching for.

This article is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment of any medical condition.

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